Gout and the medications used for the treatment of gout worsen its comorbidities as well as patients’ perceptions of their quality of life.
Gout leads many patients to report a sense of body failure and a negative effect on social roles. Also, loss of identity-associated performance is progressive in patients who have gout.
The most common inflammatory arthritis, gout has been linked to obesity and the metabolic syndrome as well as associated comorbidities, such as heart disease, hypertension, diabetes, sleep apnea, and heart failure.
Jasvinder Singh at the University of Alabama at Birmingham pointed out that little is known about how gout affects the known comorbidities and their outcomes and that published qualitative research has focused on gout’s effect on quality of life and has under-represented women.
Dr Singh sought to shed light using a trajectory model developed by Corbin and Strauss to form a qualitative description of the effect gout has on comorbidities.
He presented his findings in a recent Arthritis Research & Therapy article.
A nominal group study was conducted by looking at 45 patients with gout in 9 nominal groups. The trajectory model assessed body (organ system and function), biographical time (explicit narrative that gives meaning and purpose to a person’s life), and conceptions of self (role identity, social identity). The 3 components were reported as answers to the question, “How does gout or its treatment affect your other conditions and their treatment?”
The effects of gout or gout treatment on comorbidities and their management included the following:
• Three groups rated the interaction of gout medications with medications for other medical conditions as a top concern.
• Seven groups rated gout’s effect in worsening medical comorbidities, including hospitalizations, as a high concern.
• Three groups cited worsening anxiety and depression as a top concern.
• Three groups considered changes in diet as a primary concern.
The Division of Rheumatology at the University of Alabama at Birmingham provided funding.
Singh JA. “Gout and comorbidity: a nominal group study of people with gout.” Arthritis Res Ther. 2017 Sep 15;19(1):204. doi: 10.1186/s13075-017-1416-1418.