Patients with tophaceous gout rarely develop ulcers, but when they do occur, these ulcers can be difficult to treat. This case study explores the diagnosis of and treatment options for patients with ulcerated tophaceous gout.
Diagnosing gout can be vexing. Most of the time, the diagnosis is made in the primary care setting where physicians diagnose gout by following one of six classification criteria, with the most widely used one being the 1977 American Rheumatism Association criteria.
Four trials of moderate-quality evidence found no significant improvement in pain control in acute gout with NSAIDs vs COX inhibitors. But there was evidence that patients stopped NSAIDs early because of adverse events.
Gout attacks really do occur more often at night, and here is proof. Theories abound as to why, but effective prophylactic treatments to reduce the risk of nocturnal exacerbations appear to be just what the doctor ordered.
A large population study shows that people with gout may have a reduced risk of dementia -– including Alzheimer’s disease. This is a significant finding and may support theories that uric acid has antioxidant properties and possible neuroprotective effects.
Effective treatment for gout management does exist, but without patient compliance, gout exacerbations continue to be common. Here: strategies to get buy-in from the patient.
Calcium pyrophosphate deposition disease is many times more common than rheumatoid arthritis, but rarely studied and difficult to diagnose. Here an expert rheumatologist offers the basics for management today and prospects for the future.
Expert rheumatologists examine patterns of treatment failure in gout, in light of six recent guidelines on the condition. This brief slide show based on their review summarizes basics about the guidelines and the clues to optimal treatment, linking to the review itself.
New research confirms that taking allopurinol during active gout does not prolong the flare, and genetic studies reveal a new factor in allopurinol sensitivity.
Three eminent rheumatologists have posted their comprehensive textbook of rheumatology online, open-access and free. They are calling it Rheumaknowledgy.