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Osteoporosis

Best of EULAR 2014

What you missed by not going to Paris this year, other than great wine and fresh croissants: Sex (and gout). Smoking (bacteria, and RA). Pain relief (and its importance to the success of RA medication). A virus (papilloma, and JIA). And yet more ...

Osteoporosis

A quiz in JAMA uses a case with discordant DXA results to discuss the options in assessment of hip fracture risk in osteoporosis, describing their advantages and drawbacks.

Bisphosphonates offer women no protection against breast cancer but do help prevent fractures related to osteoporosis.

Eliglustat has a better safety profile than the existing approved oral drug for type 1 Gaucher disease, and is easier to take than enzyme replacement therapy.

Whatever is causing this woman's hip pain, her x-ray looks quite severe. The diagnosis was correct 40 years ago, but it couldn't be treated effectively then. What's the problem?

For the success of total hip replacements, 35 is the magic number, a very large Canadian study finds. Procedures done by surgeons with lower volumes per year have much greater failure risks.

Among women with osteoporosis randomized to discontinue bisphosphonates, results of bone mass testing in subsequent years were unrelated to future fracture risk. This undercuts guidelines and even a law.

(AAOS 2014) Older women with comorbidities are at greatest risk for revision surgery after total knee arthroplasty, a nationwide study shows. Another large analysis shows an interesting quirk about the role of osteoporosis: Bisphosphonates help, but only in some circumstances.

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