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Central Obesity, the Liver and Heart in the Psoriatic Patient

Central Obesity, the Liver and Heart in the Psoriatic Patient

  • (Psoriasis ©Artemidapsy/Shutterstock.com)
    (Psoriasis ©Artemidapsy/Shutterstock.com)
  • Ryan C, Kirby B. Psoriasis is a systemic disease with multiple cardiovascular and metabolic comorbidities. Dermatol Clin. 2015;33:41-55. Voiculescu VM, Lupu M, Papagheorghe L, Giurcaneanu C, Micu E. Psoriasis and Metabolic Syndrome - scientific evidence and therapeutic implications. J Med Life. 2014;7:468-71. Ogdie A, Schwartzman S, Eder L, Maharaj AB, Zisman D, Raychaudhuri SP, et al. Comprehensive treatment of psoriatic arthritis: managing.comorbidities and extraarticular manifestations. J Rheumatol. 2014;41:2315-22.
  • Citations 23-25 from André Vicente Esteves de Carvalho, Ricardo Romiti, Cacilda da Silva Souza, et al. "Psoriasis comorbidities: complications and benefits of immunobiological treatment," Anais Brasileiros de Dermatologia. November/December 2016. http://dx.doi.org/10.1590/abd1806-4841.20165080
  • Citations 28-30 from André Vicente Esteves de Carvalho, Ricardo Romiti, Cacilda da Silva Souza, et al. "Psoriasis comorbidities: complications and benefits of immunobiological treatment," Anais Brasileiros de Dermatologia. November/December 2016. http://dx.doi.org/10.1590/abd1806-4841.20165080
  • Obesity (©Design36/Shutterstock.com)
    Obesity (©Design36/Shutterstock.com)
  • Citations 31-32 from André Vicente Esteves de Carvalho, Ricardo Romiti, Cacilda da Silva Souza, et al. "Psoriasis comorbidities: complications and benefits of immunobiological treatment," Anais Brasileiros de Dermatologia. November/December 2016. http://dx.doi.org/10.1590/abd1806-4841.20165080
  • Citations 33-35 from André Vicente Esteves de Carvalho, Ricardo Romiti, Cacilda da Silva Souza, et al. "Psoriasis comorbidities: complications and benefits of immunobiological treatment," Anais Brasileiros de Dermatologia. November/December 2016. http://dx.doi.org/10.1590/abd1806-4841.20165080
  • Citations 33-36 from André Vicente Esteves de Carvalho, Ricardo Romiti, Cacilda da Silva Souza, et al. "Psoriasis comorbidities: complications and benefits of immunobiological treatment," Anais Brasileiros de Dermatologia. November/December 2016. http://dx.doi.org/10.1590/abd1806-4841.20165080
  • Citations 33, 34, 45, 49 from André Vicente Esteves de Carvalho, Ricardo Romiti, Cacilda da Silva Souza, et al. "Psoriasis comorbidities: complications and benefits of immunobiological treatment," Anais Brasileiros de Dermatologia. November/December 2016. http://dx.doi.org/10.1590/abd1806-4841.20165080
  • Citations 10, 51, 52 from André Vicente Esteves de Carvalho, Ricardo Romiti, Cacilda da Silva Souza, et al. "Psoriasis comorbidities: complications and benefits of immunobiological treatment," Anais Brasileiros de Dermatologia. November/December 2016. http://dx.doi.org/10.1590/abd1806-4841.20165080
  • Cardiovascular disease (©Lightspring/Shutterstock.com)
    Cardiovascular disease (©Lightspring/Shutterstock.com)
  • Citations 55, 56, 57 from André Vicente Esteves de Carvalho, Ricardo Romiti, Cacilda da Silva Souza, et al. "Psoriasis comorbidities: complications and benefits of immunobiological treatment," Anais Brasileiros de Dermatologia. November/December 2016. http://dx.doi.org/10.1590/abd1806-4841.20165080
  • Fatty livery disease (©MagicMine/Shutterstock.com)
    Fatty livery disease (©MagicMine/Shutterstock.com)
  • Citations 15, 75 from André Vicente Esteves de Carvalho, Ricardo Romiti, Cacilda da Silva Souza, et al. "Psoriasis comorbidities: complications and benefits of immunobiological treatment," Anais Brasileiros de Dermatologia. November/December 2016. http://dx.doi.org/10.1590/abd1806-4841.20165080
  • André Vicente Esteves de Carvalho, Ricardo Romiti, Cacilda da Silva Souza, et al. "Psoriasis comorbidities: complications and benefits of immunobiological treatment," Anais Brasileiros de Dermatologia. November/December 2016. http://dx.doi.org/10.1590/abd1806-4841.20165080

Psoriasis is associated with an extensive list of comorbidities ranging from erectile dysfunction to bronchial asthma. But there are three that are exponentially more common than others:  Metabolic syndrome, cardiovascular disease and fatty liver disease. In this slideshow, we highlight a Brazilian study that examines the effects of treatment with infliximab, adalimumab, etanercept and ustekinumab in psoriasis patients with these three comorbidities.

 

References: 

André Vicente Esteves de Carvalho, Ricardo Romiti, Cacilda da Silva Souza, et al. "Psoriasis comorbidities: complications and benefits of immunobiological treatment," Anais Brasileiros de Dermatologia. November/December 2016. http://dx.doi.org/10.1590/abd1806-4841.20165080

 

 

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