The incidence of cardiovascular comorbidities and autoimmune diseases is significantly higher among patients with psoriatic arthritis than among matched controls, a large, retrospective, US-based claims study has shown.
The increased incidence of comorbidities is accompanied by higher rates of all-cause and cardiovascular-related hospitalizations, according to results published in the Journal of Managed Care & Specialty Pharmacy.
“Understanding these comorbidity profiles may provide insight on the effect of comorbid conditions on disease management, treatment choices, and health care burden associated with psoriatic arthritis,” investigator Jeffrey Kaine, MD, of the Sarasota Arthritis Research Center in Florida, and colleagues wrote in the report.
Many previous studies of the comorbidity burden associated with psoriatic arthritis have been based on small sample sizes, and few used real-world data from claims databases, according to Dr. Kaine and co-authors.
Kaine J, Song X, Kim G, Hur P, Palmer JB. Higher incidence rates of comorbidities in patients with psoriatic arthritis compared with the general population using U.S. administrative claims data. Manag Care Spec Pharm. 2018 Apr 25:1-11.
Polachek A, Touma Z, Anderson M, Eder L. Risk of cardiovascular morbidity in patients with psoriatic arthritis: a meta-analysis of observational studies. Arthritis Care Res. 2017;69:67-74.