Rheumatoid Arthritis

New Biologics at EULAR 2014: Stop, or Wait?

A German rheumatologist attending the European Union League Against Rheumatism's annual meeting in Paris took progress notes on new biologics-in-testing. What's moving ahead and what's stalled? He provides a chart with a handy visual key.

Rheumatoid Arthritis

A large study of veterans reveals factors that predict which people starting methotrexate for rheumatic diseases after the age of 65 will quickly begin to show signs of liver damage.

Being overweight or obese not only increases the risk of rheumatoid arthritis developing in the first place; it also makes RA worse and decreases chances for remission.

A new auto-injectable form of methotrexate offers 10 dosage options. Is this an important advantage for medication management and adherence over the four already available?

Adalimumab (Humira) may alter production of tumor necrosis factor-alpha in rheumatoid arthritis patients, returning TNFα levels almost to normal. A study looking at antibodies against the drug in psoriatic arthritis found no clear evidence of an effect.

An IL4 fusion protein has completely resolved rheumatoid arthritis in a mouse study using a standard collagen-induced model of the disease.

The link between fatigue and disease activity in inflammatory arthritis appears not to be as simple as previously assumed.

About half of rheumatoid arthritis patients don't understand enough information to make intelligent treatment choices. Here's how to help.


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