Lupus: 3 New Things
Two recent studies underscore the key role of interferon in SLE; a third trial identifies a link between undiagnosed vertebral fractures and organ damage in women with lupus.
References1. Md Yusof MY, Psarras A, El-Sherbiny YM, et al. Prediction of autoimmune connective tissue disease in an at-risk cohort: prognostic value of a novel two-score system for interferon status. Ann Rheum Dis. Published online first: 21 June 2018. doi: 10.1136/annrheumdis-2018-213386.2. Kato Y, Park J, Takamatsu H, et al. Apoptosis-derived membrane vesicles drive the cGASâSTING pathway and enhance type I IFN production in systemic lupus erythematosus. Ann Rheum Dis. Published online first: 26 June 2018. doi: 10.1136/annrheumdis-2018-212988.3. Shkireeva S, Lesnyak O, Zotkin E. Influence of undiagnosed vertebral fractures on organ damage in women with systemic lupus erythematosus. Ann Rheum Dis. 2018;77:405. Abstract THU0377.
