This information is brought to you by Rheumatology Network and is not sponsored by, nor a part of, the American College of Rheumatology.
New guidelines have been drafted for the treatment of juvenile idiopathic arthritis (JIA), specifically addressing therapeutic approaches for non-systemic polyarthritis, sacroiliitis, and enthesitis.
The draft guidelines were presented at the 2018 American College of Rheumatology (ACR)/Association of Rheumatology Health Professionals (ARHP) Annual Meeting in Chicago, Illinois, on October 21 by Timothy Beukelman, MD, Associate Professor of Pediatrics at the University of Alabama at Birmingham. Dr Beukelman was the lead author of the previous 2011 ACR Recommendations for the Treatment of JIA and is a member of the core team developing the new treatment guidelines.
The ACR was motivated to update the guidelines in part because of developments in polyarthritis, including recently approved therapies and new studies about the effects of initial treatment choices. There has also been an increased emphasis on sacroiliitis, and the previous recommendations did not address enthesitis. The new recommendations are pending full approval from the ACR and the Arthritis Foundation.
Phase 1 of updating the guidelines used the GRADE (Grading of Recommendations Assessment, Development and Evaluation) methodology. The draft recommendations are based on published evidence, patient input, and voting panel experience with a requirement of 70% consensus.
A strong recommendation was issued when the panel was confident that the desirable effect of intervention outweighs the undesirable effects in almost all patients. A conditional recommendation was issued when the desirable effects probably outweigh undesirable effects in a majority of patients.
Next: Polyarthritis recommendations
3S016 ACR: Biologic Classification of JIA, 2018 Update of the ACR Treatment Guidelines for JIA. Presented at: 2018 ACR/ARHP Annual Meeting; October 20-24; Chicago, Illinois.