Rheumatoid arthritis patients who achieve low disease activity on tofacitinib in combination with methotrexate, should be able to discontinue methotrexate safely and without significant worsening of disease activity, especially if they are having trouble tolerating it, new research shows.
Gregory M. Weiss, M.D.
When considering the evidence, it appears that rather than it being a discrete clinical entity with a unique cause, rheumatoid arthritis (RA) is likely a syndrome that represents a common endpoint for a number of different causative agents.
Low-dose interleukin-2 (IL-2) was found to be safe and well tolerated in a phase 1 and 2a trial of 12 patients with systemic lupus erythematosus (SLE). The treatment may be beneficial in reducing disease activity, researchers report in Sept. 1 issue of The Lancet Rheumatology.
A new study published in the journal Arthritis & Rheumatology finds there may be a genetic explanation for the development of systemic lupus erythematosus (SLE) in African American women.
Updated treatment recommendations have been issued for ankylosing spondylitis and non-radiographic axial spondyloarthritis. There are 86 recommendations. In this slideshow, we highlight those categorized as "strongly recommended."
Review shows inconsistencies in infliximab concentrations for patients with spondyloarthritis. More research is needed to determin optimal dosages to achieve a clinical response in spondyloarthritis.
Modern pharmacologic therapies for rheumatoid arthritisare effective in controlling inflammation and preventing bone erosions however, a multitude of factors are likely to blame for ongoing bone loss in rheumatoid arthritis.
Temporal artery biopsy is a useful test for diagnosing giant cell arteritis but may miss some cases, research shows.
Pregnant women with systemic lupus erythematosus often discontinue their lupus medications during pregnancy despite recommendations to continue them.
Plasma microbial translocation may play a role in the development of autoantibodies in systemic lupus erythematosus, researchers find. The discovery may lead to new treatments in lupus.