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Author | Jack Arnold, MBBS, MRCP

Jack Arnold, MBBS, is a clinical research fellow working within Dr. Edward Vital's lupus team at the Leeds Centre of Rheumatic and Musculoskeletal Medicine. He graduated Distinction in Clinical Sciences from University College London in 2015 and has previously worked as a clinical tutor for Harris Manchester College Oxford. His work primarily focuses on systemic lupus erythematosus (SLE), antineutrophil cytoplasm antibodies (ANCA)-associated vasculitis and new approaches to the classification of autoimmune connective tissue diseases.

Articles

Think Fast! Using Machine Learning Approaches to Identify Predictors of Adverse Pregnancy Outcomes in SLE

Article

Findings demonstrate the utility of machine learning in aiding clinical risk stratification within a complex patient cohort.

Long-Term Glucocorticoid Therapy in SLE and Infective Sequelae: A Faustian Pact

Article

In SLE, higher doses of prednisolone and the use of immunosuppressive agents, such as cyclophosphamide, have been associated with higher rates of infective sequelae.

Off Target: The Long-Term Sequelae of Inadequate Disease Control in SLE

Article

As treatment options expand in SLE with an increasing number of targeted therapeutics, we can be optimistic about the potential to improve disease outcomes.

Class III/IV Lupus Nephritis Shows an Association with High Serum Type 1 Interferon Levels

Article

The utility of calculating interferon scores in SLE has generated considerable discourse amongst rheumatologists.

Lupus Nephritis: TULIP-LN Hints at a Blossoming Role for Anifrolumab

Article

In the double blinded study, patients were randomized to receive anifrolumab (300mg monthly), an intensified regimen of 3 x 900mg doses followed by 300mg monthly, or standard of care therapy with mycophenolate mofetil and oral glucocorticoids.

TeleLupus in the Context of COVID-19: Is There a Long-Term Role for Remote Consultation in How We Manage Lupus Patients?

Article

Telemedicine is an evolving and helpful tool in how rheumatologists manage their outpatient cohort. However, careful distinction of who can continue to be managed remotely is crucial.