Intravenous administration of ketamine in patients undergoing total knee or hip arthroplasty is safe and effective for postoperative pain relief and the reduction of morphine consumption without increasing the risk of gastrointestinal or psychotic adverse effects, say researchers writing in the BMJ Open last month.
Secukinumab (Cosentyx, Novartis) provided sustained low rates of radiographic progression through 52 weeks in patients with active psoriatic arthritis, say researchers writing in Rheumatology this month.
Almost 15 percent of patients with inflammatory bowel disease showed evidence of excessive steroid use or dependency, and in half of these cases this excess was potentially avoidable, say researchers writing in Alimentary Pharmacology & Therapeutics this month.
Intra-articular corticosteroid injections for relief of the pain of hip or knee osteoarthritis may be harmful in some patients with at-risk conditions or may cause complications that are not well understood, say researchers writing in Radiology this month.
More than 50 percent of early inflammatory arthritis patients wait too long for physician referrals and specialist appointments, according to the latest figures released from the British Society for Rheumatology’s National Early Inflammatory Arthritis Audit.
Among patients with systemic rheumatic diseases, the risk of opportunistic infections was highest in those with polymyositis/dermatomyositis, say researchers writing in Arthritis Research & Therapy this month.
Exposure to industrial emissions of fine particles matter and sulfur dioxide are associated with the presence of anti-citrullinated protein antibodies (ACPA), a characteristic biomarker for rheumatoid arthritis, according to a study presented at the annual meeting of the American College of Rheumatology in Atlanta on November 12.
The U.S. Food and Drug Administration has approved ustekinumab (Stelara, Janssen) for the treatment of adults with moderately to severely active ulcerative colitis, a condition that affects approximately 910,000 adults in the U.S.
Patients with psoriatic arthritis have twice the rate of joint surgery when compared with the general population, with one-third of patients with this condition undergoing joint surgery, say researchers writing in Annals of the Rheumatic Diseases this month.
Adalimumab (Humira, AbbVie) exposure in pregnancy is not associated with an increased risk for major and minor structural birth defects, spontaneous abortion, pre and post-natal growth deficiency, serious or opportunistic infections and malignancies, say researchers writing in PLOS ONE this month.