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Gout
The Rheumatology Network gout clinical focus page provides information on the latest gout news, study and clinical trial findings, and clinical guideline updates. We feature expert interviews with leading physicians and investigators, articles, videos, podcasts, and breaking FDA approvals for gout drugs.
Robert Terkeltaub, MD: Safety and Efficacy of Tigulixostat in Gout Treatment
November 23, 2021
Robert Terkeltaub, MD, explains the results from a phase 2, dose-finding study to determine the safety and efficacy of tigulixostat in patients with gout.
Jeff Peterson, MD: Majority of Patients With Gout Achieved Complete Response Rate With Combination Pegloticase and Methotrexate
November 11, 2021
Jeff Peterson, MD, discusses his study determining the complete response rate of pegloticase in conjunction with methotrexate.
Kazuki Yoshida, ScD: Gout Treatment Strategies Regarding Cardiovascular Outcomes
November 05, 2021
Kazuki Yoshida, MD, MPH, ScD, discusses his ACR presentation entitled, “Comparative Safety of Gout "Treat-to-target" and "Usual Care" Treatment Strategies on Cardiovascular Outcomes Using Observational Data: Causal Inference Approach.”
Patients With Gout at Increased Risk for Lower Extremity Amputation
November 04, 2021
Investigators analyzed comorbidities, such as diabetes, which has been historically associated with gout, to determine what role, if any, they played in increasing the risk of lower extremity amputation.
Aaron Broadwell, MD: Immunomodulation and Pegloticase Therapy for Patients With Gout
November 03, 2021
Aaron Broadwell, MD, discusses his upcoming ACR study entitled, “Concomitant immunomodulation and pegloticase therapy: experiences with a variety of immunomodulatory agents in two community rheumatology practices.”
Sarah Stewart, PhD: Long-Term Gout Flare Prevention
October 01, 2021
Sarah Stewart, PhD, discusses her study entitled "What Represents Treatment Efficacy in Long-term Studies of Gout Flare Prevention? An Interview Study of People With Gout."
Single Serum Urate Measurements Deemed Unreliable for Identifying Hyperuricemia
September 16, 2021
Hyperuricemia is associated with vascular, cardiac, and renal disease, as well as gout. However, the reliability of a single measurement in defining hyperuricemia is unclear.
Obstructive Sleep Apnea Linked to Gout
September 10, 2021
“There is likely to be a bidirectional relationship between sleep and gout, as gout flares may be influenced by circadian rhythms, and sleep quality is likely to be influenced by gout flares,” investigators explained. “Given the morbidity associated with sleep problems, we should be vigilant regarding sleep health in our patients with gout.”
Brian LaMoreaux, MD, MS: Combating the Stigma of Gout
August 18, 2021
The stigma surrounding gout has contributed to the general unease patients have about their condition.
Brian LaMoreaux, MD, MS: Improving Outcomes for Patients With Gout
August 11, 2021
Brian LaMoreaux, MD, MS, discusses the recent study entitled, "Improving outcomes for patients hospitalised with gout: a systematic review."