Osteoarthritis

 

Study Highlights Racial Disparities in Knee OA Treatment

September 22, 2020

Black patients with knee osteoarthritis have worse outcomes than their white counterparts, shows a new study.

Bisphosphonate Use Associated with Increased Fracture Risk

September 16, 2020

Bisphosphonate use, especially for more than five years, is associated with an increased risk of atypical femoral fractures, but this risk falls considerably after discontinuation, according to a Nationwide Danish an analysis and review presented on September 13 at the American Society for Bone and Mineral Research (ASBMR) annual meeting which was held virtually.

Teriparatide for Bone Formation in Hip Fractures

September 16, 2020

Teriparatide, a recombinant human parathyroid hormone analog [rhPTH(1-34)] approved for women and men with osteoporosis, has been shown to renew bone tissue in patients with femoral neck fractures of the hip, according to research presented at the American Society for Bone and Mineral Research (ASBMR) annual meeting which was held this week.

Vitamin D and Fish Oil Fail Osteoarthritis Trial

June 25, 2020

New research published in Arthritis and Rheumatology shows that vitamin D and marine omega‐3 fatty acids (n‐3 FA) do not offer long-term relief from knee pain, stiffness or function in older adults with chronic knee pain.

EULAR Issues Recommendations for Knee OA Platelet-Rich Plasma Injections

June 11, 2020

An expert consensus on the first clinical practice recommendations for platelet-rich plasma (PRP) injections in knee osteoarthritis was presented at the European Congress of Rheumatology annual meeting.

Study Shows Footwear Relieves Osteoarthritic Knee Pain

May 27, 2020

A new study shows that biomechanical footwear improved osteoarthritis knee pain at 24 weeks as compared to patients in a control group who wore traditional footwear. The results, although statistically significant, need to be replicated to prove clinical importance, researchers reported in JAMA.

Osteoarthritis Risk Intensifies With Epigenetics

May 13, 2020

The risk for osteoarthritis has been linked to a number of genes that are susceptible to epigenetic mediators, shows a new review published in Nature Reviews Rheumatology. The influence of epigenetics on osteoarthritis offers new insights on disease risk.

Are glucocorticoid injections still necessary for osteoarthritis knee pain?

May 12, 2020

In patients with knee osteoarthritis, physical therapy may improve pain and functional disability more so than intraarticular glucocorticoid injections, at one year, according to a head-to-head study published in the New England Journal of Medicine.

Fast Facts on Vitamin D, Calcium and Fracture

February 07, 2020

In this slideshow we highlight some key facts about the use of supplements to prevent fracture in women and men over the age of 50. Existing treatment guildelines recommend a combination approach with vitamin D and calcium, but some clinical trials are not entirely in agreement. Learn more in this slideshow.

Low-Dose Radiation Therapy for Knee, Hand Osteoarthritis Questioned

January 28, 2020

There is insufficient evidence to support long-term effects on pain and functioning of low-dose radiation therapy for hand and knee osteoarthritis, say researchers writing in The Lancet Rheumatology.

Motion Tests Essential for an Osteoarthritis Diagnosis

January 28, 2020

Simple hip motion tests and observing for pain during that motion were helpful in identifying patients most likely to have hip osteoarthritis on plain radiography, say researchers recently writing in the Journal of the American Medical Association.

Drug and Nondrug Approaches for Treating Osteoarthritis

January 10, 2020

Updated treatment guidelines for hand, hip and knee osteoarthritis have been issued. In this slideshow, we highlight recommendations for the use (or not) of drug and nondrug treatments. These include strong recommendations for standard treatment options, such as weight loss and Tai Chi, and strong recommendations against treatments with pharmacologicals, such as glucosamine and chondroitin sulfate (except for hand osteoarthritis). Learn more in this slideshow.

Tai-Chi, Topical Capsaicin Among the New Treatment Recommendations for Osteoarthritis

January 08, 2020

The American College of Rheumatology (ACR), in partnership with the Arthritis Foundation, has issued treatment guidelines for osteoarthritis of the hand, hip and knee. This is the first update since 2012.

Sprifermin Improves Cartilage Thickness, but Clinical Benefit Uncertain

December 11, 2019

Intra-articular administration of sprifermin statistically increases total femorotibial joint cartilage thickness in individuals with symptomatic radiographic knee osteoarthritis, but the clinical importance and duration of the effect are uncertain, say researchers writing recently in JAMA.

Methotrexate Controls Joint Damage in Hand Osteoarthritis, Small Study Shows

November 18, 2019

The first-ever study designed to assess the effectiveness of methotrexate on hand osteoarthritis finds that while the treatment did not demonstrate superior efficacy over placebo on pain or function, it did significantly reduce the progression of joint damage.

Treatment Guidelines for Hand Osteoarthritis

November 18, 2019

In this slideshow, we revisit the "American College of Rheumatology 2012 Recommendations for the Use of Nonpharmacologic and Pharmacologic Therapies in Osteoarthritis of the Hand, Hip, and Knee." 

Researchers Try to Reverse the Aging Process for Arthritic Joints

November 13, 2019

ACR Annual Meeting:  Single intra-articular doses of UBX0101 of up to 4 mg were well-tolerated by patients with painful knee osteoarthritis, according to a study presented at the annual meeting of the American College of Rheumatology in Atlanta on November 12. The treatment is in development, but if it pans out, it may reduce the effects aging on arthitic joints.

Intravenous Ketamine Offers Postoperative Pain Relief After Total Knee, Hip Arthroplasty

November 05, 2019

Intravenous administration of ketamine in patients undergoing total knee or hip arthroplasty is safe and effective for postoperative pain relief and the reduction of morphine consumption without increasing the risk of gastrointestinal or psychotic adverse effects, say researchers writing in the BMJ Open last month.

Adverse Outcomes with Intra-Articular Corticosteroid Injections in OA

November 05, 2019

Intra-articular corticosteroid injections for relief of the pain of hip or knee osteoarthritis may be harmful in some patients with at-risk conditions or may cause complications that are not well understood, say researchers writing in Radiology this month.

First-Ever Guidance on CBD Use for Arthritic Pain

October 11, 2019

The Arthritis Foundation has just released the first CBD guidance for adults with arthritis. CBD, or cannabidiol, a plant-based compound, has become popular among people with arthritis seeking to ease chronic joint pain. Learn more in this slideshow.