Vasculitis

 

Study Questions Value of Plasma Exchange for Vasculitis

March 24, 2020

Despite the publication of previous clinical trials that showed plasma exchange could possibly be a viable treatment for patients with severe ANCA-associated vasculitis, a new study recently published in the New England Journal of Medicine shows the treatment, in combination with standard therapy, didn't improve outcomes for patients or lower fatality rates or slow the progression to end-stage kidney disease.

Image IQ: Infant with skin peeling

January 30, 2020

A 20-month-old boy with skin peeling, a strawberry red tongue and swelling of the hands and feet. Can you diagnose this patient?

FDA Approves New Treatment for Rare Pediatric Vasculitis

October 01, 2019

The U.S. Food and Drug Administration has approved rituximab (Rituxan, Genentech) for the treatment of granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA) in children 2 years of age and older in combination with glucocorticoids.

EULAR Updates Guidelines for Large Vessel Vasculitis

July 19, 2019

The European League Against Rheumatism has updated treatment guidelines for the management of large vessel vasculitis. Among the changes, the task force no longer recommends the routine use of antiplatelet or anticoagulant therapy. Learn more in this slideshow.

Picture This: New EULAR Imaging Recommendations in Large Vessel Vasculitis

March 01, 2018

Ultrasound, MRI, PET, CT, MRA, CTA: guidance here on when to use which imaging technique.

Pediatric Rheumatology: 3 New Studies

February 07, 2018

An online tool for juvenile arthritis, guidelines on childhood lupus, and good news about the response to treatment for ANCA-associated vasculitis

FDA Approves First Drug for Eosinophilic Granulomatosis With Polyangiitis

December 21, 2017

Mepolizumab gets the nod for the rare disease formerly known as Churg-Strauss syndrome.

Reduce Vasculitis Relapse With Immunosuppressive Drugs

October 11, 2017

Continuing azathioprine and prednisolone past 2 years from diagnosis was superior to withholding them.

Actemra for Giant Cell Arteritis Study Data Published

August 02, 2017

The need to find an alternative to prolonged periods of steroid therapy was addressed.

Medium-Sized Vasculitides May Be Distinct Diseases

July 17, 2017

A direct comparison of their clinical characteristics helps distinguish one from another.

FDA Approves Tocilizumab for GCA

May 24, 2017

Tocilizumab in its subcutaneous form is the first-ever drug designated for giant cell arteritis which affects 230,000 people in the U.S

Diagnosing and Treating Vasculitis: an Update

April 13, 2017

Mayo Clinic’s Dr. Eric Matteson and Dr. Sharon Chung of UCSF provide an update on advances in new treatments for vasculitis.

Efficacy of Abatacept for Treating Vasculitis

March 13, 2017

Two new studies find that abatacept plus prednisone improves duration of remission for giant cell arteritis patients, but not for Takayasu’s arteritis patients.

Gastrointestinal Involvement in Systemic Vasculitis

October 10, 2016

Gastrointestinal involvement is known to be associated with primary vasculitis. But in some cases, it may be IBD with secondary vasculitis, this review shows.

EULAR Updates Vasculitis Treatment Recommendations

July 05, 2016

The European League Against Rheumatism has updated its 2009 recommendations for the management of antineutrophil cytoplasmic antibody-associated vasculitis.

IM Journal Names Top Rheumatology Reports of 2014

May 13, 2015

Top reports chosen by Annals of Internal Medicine include several on biologics for rheumatoid arthritis and psoriatic arthritis, and mechanisms for lupus and scleroderma.

FDG-PET Useful to Resolve Doubts About GCA

May 06, 2015

A systematic review finds the technique highly sensitive and specific in diagnosing giant cell arteritis, especially useful when biopsy results are equivocal.

Cryoglobulinemia: The Basics, and Two Revelations

April 22, 2015

A review and a research study take a closer look at the small vessel disease that's generally tied to hepatitis C but may arise in autoimmune disorders. The latter finds new markers for severity.

Free For All: Rheumatology Textbook by Cush, Kavanaugh, and Stein

April 02, 2015

Three eminent rheumatologists have posted their comprehensive textbook of rheumatology online, open-access and free. They are calling it Rheumaknowledgy.

Should All Patients Get Hep B Screening Before Immunosuppressants?

March 31, 2015

About 30% of rheumatologists don't pre-test patients for hepatitis B before prescribing immunosuppressant medications. These authors offer new guidance for screening.