The Journal of Musculoskeletal Medicine Vol 27 No 5

The Use of Biologic Agents in the Geriatric Population

May 01, 2010

The aging process is difficult, involving multisystem functional decline, and the pharmacokinetics of medications are altered in older persons, resulting in increased risks. Concerns are demonstrated in case reports.

All about osteoporosis: Meeting the treatment challenge

April 29, 2010

Following the release of revised National Osteoporosis Foundation guidelines and of the World Health Organization’s fracture risk assessment tool, several pharmacological therapies have become available to help improve outcomes in patients with osteoporosis.

Achilles tendon evaluation and repair

April 29, 2010

ABSTRACT: Achilles tendon injuries are increasing as the population ages yet remains physically active later in life. Early diagnosis and management are important for good long-term outcome, but many injuries are missed or misdiagnosed on initial evaluation.

RA task force releases treatment recommendations

April 28, 2010

Remission must be the ultimate therapeutic goal for patients with rheumatoid arthritis (RA), according to an international task force that set out to develop recommendations for achieving optimal outcomes in RA in clinical practice. Treatment targets have helped improve outcomes in other areas of medicine (eg, diabetes mellitus, hyperlipidemia, and hypertension), the investigators noted, but treatment targets had not been defined for RA, even in light of major treatment changes in recent years (see Box, “Sea change in RA treatment,” below). Therefore, using evidence obtained from a systematic literature review and expert opinion, they formulated a consensus finding that resulted in 10 recommendations for treatment to target in RA.

Injury prevention campaign targets young athletes

April 27, 2010

The STOP Sports Injuries campaign was launched recently by a coalition of organizations to educate athletes, parents, trainers, coaches, and health care professionals about the rapid increase in youth sports injuries currently taking place, the steps needed to reverse the trend, and the need to keep young athletes healthy. Program components include teaching proper prevention techniques and discussing the need for open communication. Featured are public service announcements; a Web site with information about sport-specific injuries; and “The Pledge” with which participants agree to become advocates for sports safety and adopt appropriate preventive measures.

RA carries “social costs” as well as economic burden

April 26, 2010

The deleterious effects of rheumatoid arthritis (RA) on employment and productivity are clearly associated with a burden on the US economy. However, RA also has significant “social costs” for both employed and unemployed persons.

Neuromuscular training puts a stop to lower limb injuries

April 26, 2010

Proprioceptive and neuromuscular training help reduce the incidence of some types of injuries among adolescent and young adult athletes participating in sports that involve pivoting. Balance exercises and multi-interventional training programs (balance plus strength and flexibility maneuvers) may be particularly effective in preventing basketball, soccer, handball, and floorball injuries.

Ankylosing Spondylitis Best Identified With Erosions on MRI

April 26, 2010

For patients who have ankylosing spondylitis (AS), radiographic assessment of the sacroiliac joint with MRI is the cornerstone of evaluation and treatment. Erosions alone-rather than bone marrow edema or contrast medium enhancement-are the most disease-specific measurable imaging findings in sacroiliac MRI of patients with AS in clinical practice.

Cardiovascular benefits with statins outweigh diabetes risk

April 26, 2010

There is a small absolute risk of diabetes mellitus (DM) in patients who receive statin therapy, but that risk is easily outweighed by the benefit that statins provide in reducing cardiovascular (CV) events. Therefore, clinical practice does not need to change for patients with moderate or high CV risk or existing CV disease.

Improve microvascular dysfunction and RA, reduce cardiovascular risk, with antirheumatics

April 26, 2010

Microvascular dysfunction correlates with systemic inflammation, which plays a key role in cardiovascular disease (CVD) as well as in rheumatoid arthritis (RA). In patients who have active RA, microvascular dysfunction improves in those who respond to antirheumatic treatment; aggressive control of RA disease activity helps avoid further joint damage and disability and may reduce CVD risk.