The Journal of Musculoskeletal Medicine Vol 27 No 9

Defining Osteoarthritis: What It Is, and What It Is Not

September 09, 2010

Synovial inflammation in osteoarthritis (OA) is secondary to mechanical damage to the articular cartilage and bone. OA often is said to be a disease of weight-bearing joints, but it is more appropriate to consider them as load-bearing joints. OA is the failure of an organ, the synovial joint.

Managing Foot and Ankle Injuries in Athletes

September 09, 2010

Physicians who treat athletes with traumatic foot and ankle injuries should know when to order special imaging studies, determine whether injuries can be managed in the office or require referral, and return the athlete to sports activity quickly. For simple ankle sprains, plain x-ray films usually are not indicated; functional rehabilitation is a first-line treatment.

Hepatitis C–Related Arthropathy: Diagnostic and Treatment Considerations

September 09, 2010

Hepatitis C–related arthropathy is one of the most common extrahepatic manifestations of hepatitis C virus (HCV) infection. Although symptoms can be disabling, the prognosis typically is benign. Patients who have atypical chronic inflammatory arthritis with an unknown cause should be evaluated for HCV infection.

Revised RA classification criteria allow for earlier study of treatments

September 08, 2010

Newly revised classification criteria for rheumatoid arthritis (RA) will allow for the study of treatments at much earlier disease stages and lead to better patient outcomes, according to the American College of Rheumatology (ACR), which created the new criteria in collaboration with the European League Against Rheumatism (EULAR).

New treatment for severe vasculitis?

September 07, 2010

A new strategy for treating patients who have antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis, a severe form of vasculitis, provides the same benefits as the current standard of care used for more than 40 years but requires less frequent treatments.

ACL update: Lubrication key to preventing osteoarthritis after injury

September 06, 2010

The researchers used animal models with torn ACLs to test 3 types of fluids that could be injected into the joints to serve as a substitute for lost synovial fluid: human synoviocyte lubricin that was created in a culture and then purified to be

Quality of life in women takes a hit with fractures

September 05, 2010

Women with osteoporosis who previously had fractures experience a significant reduction in health-related quality of life similar to or worse than that experienced by patients with diabetes mellitus

Reaching RA remission is a realistic goal

September 03, 2010

Remission is a realistic goal for patients with rheumatoid arthritis (RA), especially with intensive combination treatment regimens provided early in the disease course. The Disease Activity Score 28 (DAS28) remission criteria appear to be easiest to achieve.

Lupus in Men: All in the Genes?

September 03, 2010

There may be genetic susceptibility factors for systemic lupus erythematosus (SLE) that act only in men. In about 1% of families with SLE, all the patients with SLE are male and the women universally have positive antinuclear antibodies; also, men with SLE have more children with SLE than do women with SLE.

Cardiometabolic risk in youths: Fatness outweighs fitnes

September 03, 2010

Both fatness and fitness are associated with cardiometabolic risk factors in American youths, but fatness associations are stronger. Although maintaining high levels of fitness and preventing obesity may affect cardiometabolic risk factors positively, obesity prevention may have greater benefit.

Ultrasonographic guidance boosts joint injection accuracy

September 03, 2010

Corticosteroid injection in the joints of patients with inflammatory arthritis results in significant alleviation of symptoms and improvement in functional status. Ultrasonography (US)-guided injections are significantly more accurate than clinical examination (CE)-guided injections.

RA outcomes improve with close monitoring

September 03, 2010

Outcomes in patients with rheumatoid arthritis (RA) are improved with systematic monitoring of disease activity in daily practice. Needed are a tight control strategy aimed for at least low disease activity and frequent follow-up.