Musculoskeletal pain is common. In one analysis, 33% of adults reported musculoskeletal pain from overuse as a chief complaint. Morbidity resulting from musculoskeletal pain contributes to 29% of lost workdays because of illness and is second only to cardiovascular disease in terms of economic burden
Although hip and knee arthroplasty often are successful in restoring function and minimizing pain in patients with osteoarthritis, venous thromboembolic disease-encompassing deep vein thrombosis (DVT) and pulmonary embolism (PE)
Areal bone mineral density is lower in women who have a history of juvenile idiopathic arthritis (JIA). In later life, these patients may be at risk for osteoporosis complications, including fragility fractures.