Guselkumab, a selective antagonist of IL-23, went head to head with adalimumab in a year-long phase 2 trial of 293 patients with moderate to severe plaque psoriasis. A quick synopsis of the results here.
A case report describes the use of anakinra in a patient with psoriatic arthritis in whom pyoderma gangrenosum developed. The ulcer had not responded to any other therapies.
This is a case report of a patient with rheumatoid arthritis in whom interstitial lung disease (ILD) developed. ILD is one of several pulmonary complications of RA.
Here is the case of a 30-year-old man with scalp psoriasis in whom Koebner phenomenon developed at areas of developing shingles.
New study results shed light on questions about the effect of combining drugs to treat osteoporosis and what happens after a switch from one drug to another.
There is now clinical evidence to support cyclosporine and prednisolone as first line options in the treatment of pyoderma gangrenosum.
A review of ischemic optic neuropathies--arteritic and nonarteritic.
NEJM weighs weak evidence of benefit against small risk of viscosupplementation for osteoarthritic knees and recommends against it.
Adding rituximab to methotrexate improved outcomes in rheumatoid arthritis, without increasing adverse effects. There were some caveats, however.
This systemic review and meta-analysis found no significant benefit to arthroscopic knee surgery. An editorialist asks, “In light of this evidence, why is arthroscopy still so common?”