Central Obesity, the Liver and Heart in the Psoriatic Patient

March 10, 2017

In this slideshow, we highlight a Brazilian study that examines the effects of biologics on the three most common psoriasis comorbidities: Metabolic syndrome, cardiovascular disease and fatty liver disease.

Psoriasis is associated with an extensive list of comorbidities ranging from erectile dysfunction to bronchial asthma. But there are three that are exponentially more common than others:Â Metabolic syndrome, cardiovascular disease and fatty liver disease. In this slideshow, we highlight a Brazilian study that examines the effects of treatment with infliximab, adalimumab, etanercept and ustekinumab in psoriasis patients with these three comorbidities.Â

References:

AndrÃ© Vicente Esteves de Carvalho, Ricardo Romiti, Cacilda da Silva Souza, et al. "Psoriasis comorbidities: complications and benefits of immunobiological treatment," Anais Brasileiros de Dermatologia. November/December 2016. http://dx.doi.org/10.1590/abd1806-4841.20165080

(Psoriasis ©Artemidapsy/Shutterstock.com)

(Psoriasis Â©Artemidapsy/Shutterstock.com)

Ryan C, Kirby B. Psoriasis is a systemic disease with multiple cardiovascular and metabolic comorbidities. Dermatol Clin. 2015;33:41-55. Voiculescu VM, Lupu M, Papagheorghe L, Giurcaneanu C, Micu E. Psoriasis and Metabolic Syndrome - scientific evidence and therapeutic implications. J Med Life. 2014;7:468-71. Ogdie A, Schwartzman S, Eder L, Maharaj AB, Zisman D, Raychaudhuri SP, et al. Comprehensive treatment of psoriatic arthritis: managing.comorbidities and extraarticular manifestations. J Rheumatol. 2014;41:2315-22.

Citations 23-25 from AndrÃ© Vicente Esteves de Carvalho, Ricardo Romiti, Cacilda da Silva Souza, et al. "Psoriasis comorbidities: complications and benefits of immunobiological treatment," Anais Brasileiros de Dermatologia. November/December 2016. http://dx.doi.org/10.1590/abd1806-4841.20165080

Citations 28-30 from AndrÃ© Vicente Esteves de Carvalho, Ricardo Romiti, Cacilda da Silva Souza, et al. "Psoriasis comorbidities: complications and benefits of immunobiological treatment," Anais Brasileiros de Dermatologia. November/December 2016. http://dx.doi.org/10.1590/abd1806-4841.20165080

Obesity (Â©Design36/Shutterstock.com)

Citations 31-32 from AndrÃ© Vicente Esteves de Carvalho, Ricardo Romiti, Cacilda da Silva Souza, et al. "Psoriasis comorbidities: complications and benefits of immunobiological treatment," Anais Brasileiros de Dermatologia. November/December 2016. http://dx.doi.org/10.1590/abd1806-4841.20165080

Citations 33-35 from AndrÃ© Vicente Esteves de Carvalho, Ricardo Romiti, Cacilda da Silva Souza, et al. "Psoriasis comorbidities: complications and benefits of immunobiological treatment," Anais Brasileiros de Dermatologia. November/December 2016. http://dx.doi.org/10.1590/abd1806-4841.20165080

Citations 33-36 from AndrÃ© Vicente Esteves de Carvalho, Ricardo Romiti, Cacilda da Silva Souza, et al. "Psoriasis comorbidities: complications and benefits of immunobiological treatment," Anais Brasileiros de Dermatologia. November/December 2016. http://dx.doi.org/10.1590/abd1806-4841.20165080

Citations 33, 34, 45, 49 from AndrÃ© Vicente Esteves de Carvalho, Ricardo Romiti, Cacilda da Silva Souza, et al. "Psoriasis comorbidities: complications and benefits of immunobiological treatment," Anais Brasileiros de Dermatologia. November/December 2016. http://dx.doi.org/10.1590/abd1806-4841.20165080

Citations 10, 51, 52 from AndrÃ© Vicente Esteves de Carvalho, Ricardo Romiti, Cacilda da Silva Souza, et al. "Psoriasis comorbidities: complications and benefits of immunobiological treatment," Anais Brasileiros de Dermatologia. November/December 2016. http://dx.doi.org/10.1590/abd1806-4841.20165080

Cardiovascular disease (©Lightspring/Shutterstock.com)

Citations 55, 56, 57 from AndrÃ© Vicente Esteves de Carvalho, Ricardo Romiti, Cacilda da Silva Souza, et al. "Psoriasis comorbidities: complications and benefits of immunobiological treatment," Anais Brasileiros de Dermatologia. November/December 2016. http://dx.doi.org/10.1590/abd1806-4841.20165080

Fatty livery disease (©MagicMine/Shutterstock.com)

Citations 15, 75 from AndrÃ© Vicente Esteves de Carvalho, Ricardo Romiti, Cacilda da Silva Souza, et al. "Psoriasis comorbidities: complications and benefits of immunobiological treatment," Anais Brasileiros de Dermatologia. November/December 2016. http://dx.doi.org/10.1590/abd1806-4841.20165080

AndrÃ© Vicente Esteves de Carvalho, Ricardo Romiti, Cacilda da Silva Souza, et al. "Psoriasis comorbidities: complications and benefits of immunobiological treatment," Anais Brasileiros de Dermatologia. November/December 2016. http://dx.doi.org/10.1590/abd1806-4841.20165080