Smilack JD. Medical Extremes (A Compendium of Medical Records) Is Now Online. The American Journal of Medicine 2014;127(12): e41, December 2014 doi: http://dx.doi.org/10.1016/j.amjmed.2014.09.005
Inspired by the Guinness Book of World Records, the author and his colleagues published a short book of extreme measurements in medicine several years ago.
They've now turned the book into a free access web site, and are soliciting new entries for it.
The rheumatology-related entries to date are:
| Highest serum DNA titer | 1:2,560 |
| Highest serum anti-mitochondrial antibody titer | 1:640 |
| Highest serum antinuclear antibody (ANA) titer | 1:81,920 |
| Highest serum anti-streptolysin O (ASO) titer | 1:4,800 |
| Highest serum rheumatoid factor titer | 1:10,240 |
| Lowest serum complement C3[1] | 8 mg/dL |
| Lowest serum complement C4 | 2.6 mg/dL |
| Largest tophus | 7 cm x 6.3 cm x 3.3 cm; 72 gm |
