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A medical web site devoted to extremes in medicine seeks record-setting rheumatology cases.
Smilack JD. Medical Extremes (A Compendium of Medical Records) Is Now Online. The American Journal of Medicine 2014;127(12): e41, December 2014 doi: http://dx.doi.org/10.1016/j.amjmed.2014.09.005
Inspired by the Guinness Book of World Records, the author and his colleagues published a short book of extreme measurements in medicine several years ago.
They've now turned the book into a free access web site, and are soliciting new entries for it.
The rheumatology-related entries to date are:
|Highest serum DNA titer||1:2,560|
|Highest serum anti-mitochondrial antibody titer||1:640|
|Highest serum antinuclear antibody (ANA) titer||1:81,920|
|Highest serum anti-streptolysin O (ASO) titer||1:4,800|
|Highest serum rheumatoid factor titer||1:10,240|
|Lowest serum complement C3||8 mg/dL|
|Lowest serum complement C4||2.6 mg/dL|
|Largest tophus||7 cm x 6.3 cm x 3.3 cm; 72 gm|