Gout Raises Risk of Chronic Kidney Disease

November 28, 2018

British researchers build a strong case for closer monitoring of renal function in patients with gout.

Roughley and colleagues¹ in the UK have linked gout to an increased risk of stage 3 and greater chronic kidney disease (CKD). Scroll through the slides for the details of their study and the take-home points for clinicians.

NSAID, nonsteroidal anti-inflammatory drug.

Gout has been previously associated with chronic kidney disease (CKD). Unchecked, CKD can progress to end-stage renal disease and lead to the need for dialysis and even death.

CKD, chronic kidney disease; eGFR, estimated glomerular filtration rate; ULT, urate-lowering therapy.

CKD, chronic kidney disease; HR, hazard ratio; ULT, urate-lowering therapy.

CKD, chronic kidney disease; NSAID, nonsteroidal anti-inflammatory drug; ULT, urate-lowering therapy.

CKD, chronic kidney disease.

Reference

1. Roughley M, Sultan AA, Clarson L, et al. Risk of chronic kidney disease in patients with gout and the impact of urate lowering therapy: a population-based cohort study. Arthritis Res Ther. 2018;20:243. doi: 10.1186/s13075-018-1746-1.

[Editor’s note: For more information on the link between gout and chronic kidney disease, see Gout and CKD: A Common, Complicated Combination on our partner site Patient Care Online.]

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Gout Raises Risk of Chronic Kidney Disease

Gregory M. Weiss, MD