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Osteoarthritis Risk: Updates From ACR 2018

October 22, 2018
Gregory M. Weiss, MD

Recent studies identify a counterintuitive risk factor, as well as 2 predictors of accelerated knee osteoarthritis.

References1. Davis J, Ward RJ, MacKay J, et al. Effusion-Synovitis and Infrapatellar Fat Pad Edema Differentiate Accelerated Knee Osteoarthritis: Data from the Osteoarthritis Initiative [abstract]. Arthritis Rheumatol. 2018;70(suppl 10). Abstract 952. Accessed October 21, 2018.2. Funck-Brentano T, Nethander M, Moverare Skrtic S, Richette P, Ohlsson C. Bone Mineral Density Is a Causal Risk Factor for Knee and Hip Osteoarthritis: A Population-Based and Mendelian Randomization Study in the UK Biobank [abstract]. Arthritis Rheumatol. 2018;70(suppl 10). Abstract 956. Accessed October 21, 2018.This information is brought to you by Rheumatology Network and is not sponsored by, nor a part of, the American College of Rheumatology.

Two studies presented at the American College of Rheumatology (ACR 2018) annual meeting in Chicago, IL, examine differences among osteoarthritis (OA) types with regard to synovitis and bone mineral density (BMD). In the first study, Davis and colleagues discovered a pattern of early infrapatellar fat pad (IFP) edema and/or effusion-synovitis in advance of development of accelerated knee osteoarthritis (AKOA).1 In the second study, Funck-Brentano and fellow European researchers found that high bone mineral density (BMD) is a risk factor for knee and hip osteoarthritis.2 Scroll through the slides for the details of the two studies and the take-home points for clinicians.

AKOA, accelerated knee osteoarthritis; IFP, infrapatellar fat pad.

BMD, bone mineral density; CI, confidence interval; OR, odds ratio; SD, standard deviation.

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