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RA Quiz: Can you identify the indicators for aggressive rheumatoid arthritis?

Patients with severe and progressive rheumatoid arthritis are at risk for joint damage and deformities, especially of the hands, including ulnar deviation and swan neck deformities. In this quiz, we ask five questions on recognizing and treating aggressive rheumatoid arthritis.

Patients with severe and progressive rheumatoid arthritis are at risk for joint damage and deformities, especially of the hands, icluding ulnar deviation and swan neck deformities. In this quiz, we ask five questions on recognizing and treating aggressive rheumatoid arthritis.

Question One:  Erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) level, rheumatoid factor (RF) assay, antinuclear antibody (ANA) assay, and anti−cyclic citrullinated peptide (anti-CCP) are among the tests ordered when rheumatoid arthritis is suspected. But of these, which two tests are most often negative?