What underlies the apparent disparities in disease course and treatment outcomes between men and women with rheumatoid arthritis?
Reference1. Aldridge J, Pandya JM, Meurs L, et al. Sex-based differences in association between circulating T cell subsets and disease activity in untreated early rheumatoid arthritis patients. Arthritis Res Ther. 2018;20:150. doi: 10.1186/s13075-018-1648-2.
Aldridge and fellow researchers in Sweden found that there are sex-based differences in the association between T cell subsets and disease activity in rheumatoid arthritis (RA). T cells were implicated only in men with RA.1 Scroll through the slides for the details of the study and the take-home points for physicians.
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CDAI, Clinical Disease Activity Index; CRP, C-reactive protein; DAS28, disease activity score in 28 joints; ESR, erythrocyte sedimentation rate; RA, rheumatoid arthritis.