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(VIDEO) Data from an international lupus cohort shows the factors that correlate with permanent damage to renal, pulmonary, and other body systems. Some of them are modifiable.
Lupus erythematosus may have the word "systemic" in its official name, but some of the systemic damage may be preventable. This is the "important pragmatic message for practicing physicians" presented by Ian Bruce MD, professor of rheumatology at at the University of Manchester UK and current chair of Systemic Lupus International Collaborating Clinics (SLICC).
In this brief video, Dr. Bruce describes findings from an international cohort of more than 1700 lupus patients, in a study that looked at factors associated with renal, pulmonary, cardiovascular, musculoskeletal, and other kinds of systemic damage over time, as measured by the SLICC-ACR Damage Index.
Some of these factors (age, gender, ethnicity) are obviously immutable. But a number of them are amenable to intervention.
"This raises the possibility that damage in lupus patients will be potentially modifiable" by addressing these risk factors, says Dr. Bruce. The finding also has implications for the design of lupus clinical trials.