The Rheumatology Network lupus clinical focus page provides information on the latest lupus news, study and clinical trial findings, and clinical guideline updates. We feature expert interviews with leading physicians and investigators, articles, videos, podcasts, and breaking FDA approvals for systemic lupus erythematosus drugs.

Pregnant Women With Lupus Benefit From Multidisciplinary Clinical Pathway

May 13, 2021

As systemic lupus erythematosus (SLE) and/or antiphospholipid syndrome (APS) can cause complications during pregnancy, investigators believe it is imperative that women follow the clinical practice guidelines and receive multidisciplinary counseling before trying to conceive.

Neonatal Lupus Erythematosus Risk Not Linked to Ethnicity

April 28, 2021

“In this large, multiethnic, single-center, cohort study of children born to anti-Ro antibody positive mothers, the child’s ethnicity was not associated with NLE risk, nor specific NLE manifestations,” stated investigators.

Poor Social Determinants Linked to Worse Care and Outcomes for Patients With Lupus

April 21, 2021

While further studies are needed, the results indicate that resolving the SDoH issues, via programs like the iCMP, may decrease healthcare costs while equalizing care and outcomes for both patients with SLE and those with complex chronic conditions in general.

Fatigue in Patients With Systemic Lupus Erythematosus Linked to Anxiety and Depression

April 01, 2021

While some patients with systemic lupus erythematosus (SLE) find it beneficial to receive anti-inflammatory therapy to treat their fatigue, there is increasingly more evidence that chronic diseases increase risk of psychiatric disorders, such as anxiety and depression, which need to be treated differently.

Investigators Create Systemic Lupus Erythematosus Risk Probability Index (SLERPI) Diagnosis Tool

March 24, 2021

Currently, diagnosing a patient with systemic lupus erythematosus (SLE) is a complex process that compares potential lupus with other conditions. It can be challenging and delayed by a period of time, which increases patient uncertainty, referrals, healthcare utilization, increased flares, and organ dysfunction. In this study, machine learning (ML) via artificial intelligence tools based on patient data was used to develop an algorithm to help with SLE diagnosis.

Increased Risk for Cardiovascular Events in Women With Systemic Lupus Erythematosus

March 05, 2021

Brian Skaggs, PhD, and Maureen McMahon, MD, sat down with Rheumatology Network to discuss the results of their longitudinal study, “A Panel of Biomarkers Associates With Increased Risk for Cardiovascular Events in Women With Systemic Lupus Erythematosus.”

Asthma and COPD Linked to Worse Outcomes for Patients With Systemic Lupus Erythematosus

February 24, 2021

Investigators explored the connection between patients with systemic lupus erythematosus (SLE) and an increased risk of asthma and chronic obstructive pulmonary disease (COPD), which concurrently correlated with worse patient-reported outcomes (PROs) cross-sectionally.