Osteoarthritis

The Rheumatology Network osteoarthritis clinical focus page provides information on the latest osteoarthritis and osteoporosis news, study and clinical trial findings, and clinical guideline updates. We feature expert interviews with leading physicians and investigators, articles, videos, podcasts, and breaking FDA approvals for osteoarthritis drugs.

Denosumab Effectively Halts Erosive Progression of Hand Osteoarthritis

December 13, 2022

Improvements in GUSS, a validated tool developed to identify changes in hand osteoarthritis over time, were higher in the denosumab group when compared with placebo and the development of new erosive joints was significantly lower at week 48.

CRTAC1 Biomarker Linked to Increased Osteoarthritis Risk, Joint Replacements

October 25, 2022

“The lack of a biomarker of osteoarthritis has hindered development of effective therapies for this common disease,” investigators explained.

E Michael Lewiecki, MD: Sequential Therapy in Osteoporosis

October 20, 2022

E Michael Lewiecki, MD, discusses his CCR West presentation “Sequential Therapy in Osteoporosis: When Does the Order Matter?”

E Michael Lewiecki, MD: When is Osteopenia Osteoporosis?

October 20, 2022

E Michael Lewiecki, MD, discusses his CCR West presentation “When is Osteopenia Osteoporosis?”

Kim Bennell, PhD: Benefits of an Online Yoga Program for Patients with Knee Osteoarthritis

September 26, 2022

Kim Bennell, PhD, discusses her study “Effectiveness of an Unsupervised Online Yoga Program on Pain and Function in People With Knee Osteoarthritis: A Randomized Clinical Trial.”

BMI Reductions Linked to Lowered Risk of Developing Knee Osteoarthritis

September 22, 2022

Although results were associative rather than causative, a decrease in BMI may prevent, delay, or slow the structural defects in knee osteoarthritis.

Yoga Program Improves Physical Function in Patients with Knee Osteoarthritis

September 21, 2022

"Online interventions have the potential to reach a wide audience, allowing exercise to be undertaken from the comfort and convenience of home and thereby overcoming some of the barriers to exercise reported in the osteoarthritis population.”

Ampion Improves Pain and Function in Severe Osteoarthritis of the Knee

March 03, 2022

Aspartyl-alanyl-diketopiperazine (Ampion), an intra-articular injection, works to regulate immune responses that are connected to pain, inflammation, and joint damage in patients with osteoarthritis of the knee.

Higher BMI Linked to Greater Pain Severity in Osteoarthritis

February 10, 2022

According to the study, weight loss may be an effective strategy to prevent or treat pain in patients with hand osteoarthritis.

Duloxetine Does Not Improve Pain in Patients With Knee Osteoarthritis

January 13, 2022

While investigators were hopeful that duloxetine, an SNRI, would reduce chronic pain in patients with knee osteoarthritis, results were lackluster and clinically insignificant.