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Osteoarthritis
The Rheumatology Network osteoarthritis clinical focus page provides information on the latest osteoarthritis and osteoporosis news, study and clinical trial findings, and clinical guideline updates. We feature expert interviews with leading physicians and investigators, articles, videos, podcasts, and breaking FDA approvals for osteoarthritis drugs.
Duloxetine Does Not Improve Pain in Patients With Knee Osteoarthritis
January 13, 2022
While investigators were hopeful that duloxetine, an SNRI, would reduce chronic pain in patients with knee osteoarthritis, results were lackluster and clinically insignificant.
Mobile Health App Increases Mobility and Function in Patients With Knee Osteoarthritis
October 26, 2021
“Using the strengthening exercises with mHealth may have the potential to reduce pain, improve mobility, functional activity, and activities of daily living among knee osteoarthritis patients who are overweight or obese," investigators stated.
Overdrive Podcast: Controversies in Osteoporosis
October 25, 2021
On this month's episode of Overdrive, E Michael Lewiecki, MD, discusses recent controversies and trends in osteoporosis management, predictions for 2022, and how COVID-19 impacted the treatment landscape for rheumatologists.
Physical Activity Increases Function in Patients With Knee Osteoarthritis
October 22, 2021
A regular fitness routine was associated with less pain and stiffness, as well as an increase in functional capacity, in patients with knee osteoarthritis.
E Michael Lewiecki, MD: Controversies in Osteoporosis
October 11, 2021
E Michael Lewiecki, MD, discusses his CCR West presentations entitled, “Controversies in Osteoporosis” and “What's New in Osteoporosis for 2021?”
Philip Conaghan, MBBS, PhD: Efficacy of Tanezumab in Patients With Osteoarthritis
September 08, 2021
Philip Conaghan, MBBS, PhD, discusses his presentation entitled, “Meaningful Improvements in WOMAC Pain and Physical Function in 3 Phase 3 Trials of Tanezumab in Patients With Moderate-to-Severe Osteoarthritis: A Responder Analysis.”
Activity Monitor Usage in Patients Requiring Total Knee Replacements
September 08, 2021
Despite the benefits of physical activity, participation is low, both within the general population and among individuals with osteoarthritis (OA). Activity monitors may aid in increasing these levels in patients with OA as well as in those requiring a total knee replacement.
Q&A: Clinical, Molecular Associations With Knee Injury Outcomes
July 12, 2021
In this Q&A, corresponding author, Fiona Watt, MBBS, PhD, FRCP, discusses her study that found the combination of effusion and hemarthrosis at the time of acute knee injury is associated with adverse outcomes at 2 years post-injury.
Gene Therapy Improves Pain Management and Disease Progression for Osteoarthritis
June 24, 2021
Treatment of the osteoarthritis has been at a standstill, with short-term pain management with steroid injections considered standard care. However, a promising new therapeutic approach may help to sustain pain relief over time.
Nicholas Brisson, PhD: Machine Learning Equation Provides Predictions for Knee Osteoarthritis Outcomes
May 24, 2021
Rheumatology Network interviewed Nicholas Brisson, PhD, to discuss his recent study, “Association of machine learning based predictions of medial knee contact force with cartilage loss over 2.5 years in knee osteoarthritis." The study discovered that machine learning was able to develop an equation for predicting medial tibiofemoral contact force (MCF) peak, which supports the theory that mechanical loading directly contributes to disease progression.