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Tocilizumab added to methotrexate suppresses inflammation as compared to tocilizumab alone after inadequate methotrexate response.

Early stage RA treated with tocilizumab or tocilizumab and methotrexate realized clinical benefits with no safety concerns at two years.


Research shows that for women with autoimmune disease, the increase risk of infection during pregnancy is associated with steroids, not DMARDs.


Estimates for juvenile idiopathic arthritis differ widely depending on which set of criteria doctors use.

Oxycodone (©SteveHeap/Shutterstock.com)

The CDC recommends non-opioid alternatives for chronic pain, but some alternatives are more effective than others and some can be harmful. In this slideshow, we review the evidence.

Chronic pain (©Lightspring/Shutterstock.com)

DMARDs and surgery are unlikely to be effective as sole therapies when central pain vs. peripheral pain is suspected in lupus, RA and osteoarthritis.

(Prescriptions. ©megaflopp/Shutterstock.com)

Prescribing opioids for chronic pain may be associated with some short-term efficacy, but there may be other alternatives physicians should consider.


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