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A new guidance document from the FDA attempts to define in detail when two monoclonal antibodies are the same. It says it will not use this definition for biosimilars, but only for "orphan drugs."

The FDA has issued a safety alert warning that epidural corticosteroid injections may rarely cause serious neurological adverse events including loss of vision, stroke or paralysis, or may be fatal.

Medication adherence among gout patients is poorer than for many other chronic conditions. Authors of a systematic review point to some probable explanations.

An observational study finds that regularly drinking low-fat milk slows joint narrowing in arthritic knees. Needs confirmation, but the prospective remedy is harmless and promising.

The best news for rheumatologists from last year, in this review, involved osteoarthritis, psoriatic arthritis, and rheumatoid arthritis -- including a good way to assess cardiovascular risk in RA.

A case study in a dermatology journal discusses a stubborn case of cryoglobulinemia with unusual involvement of the iris. Rituxan resistance is increasing in this condition.

In a small placebo-controlled trial, methotrexate significantly improved pain and other symptoms of knee osteoarthritis and predictably modest adverse effects.

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