Metabolic Syndrome: How Frequent in Lupus?

May 1, 2018

Since cardiovascular disease is associated with SLE, researchers hypothesized there might be a link between the metabolic syndrome and SLE.

Reference1. Mobini M, Niksolat F, Mohammadpour RA, Dashti Dargahloo S, Marzban D. Metabolic syndrome in patients with systemic lupus erythematosus: association with disease activity, disease damage and age. Int J Rheum Dis. 2018 Apr 3. doi: 10.1111/1756-185X.13276. [Epub ahead of print]

Patients with systemic lupus erythematosus (SLE) are at increased risk for cardiovascular comorbidities, which are linked to the metabolic syndrome. Is there an association between lupus and the metabolic syndrome?

Thumb through the slides to read the details of a recent study that looked at this question as well as the take-home messages for clinicians.¹

(Image credit: ©Anna Kutukova/Shutterstock.com)

With a worldwide epidemic of obesity, there has been an increase in the prevalence of insulin resistance along with hypertension, hypertriglyceridemia, and low high-density lipoprotein cholesterol, which-when clustered together-describe the metabolic syndrome.

The researchers sought to examine the frequency of the metabolic syndrome in patients with SLE and compare it with the frequency in controls.

HAQ, Health Assessment Questionnaire; LDL-C, lowâdensity lipoprotein cholesterol.

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Metabolic Syndrome: How Frequent in Lupus?

Gregory M. Weiss, MD