Sjogren's Syndrome

 

Patients with Anti-Sjögren’s Syndrome Type A (Anti-SSA) Have Higher Risk of Neurological Involvement

March 11, 2021

There were no differences in the occurrence of clinical characteristics between the subset of patients with and without neurological involvement, however disease activity was slightly higher in patients with neurological involvement than those without. Additionally, anti-SSA antibody was significantly higher in patients with neurological involvement and anti-SSB autoantibody was lower.

If Remission Is Our Goal, Rheumatology Must Embrace the Importance of Studying New Mechanisms

January 25, 2021

Alyssa Johnsen, MD, PhD, shares her insight on the importance of understanding key pathways that drive immune-mediated diseases, which can help rheumatologists develop more potent and specific therapies for patients with rheumatic disease.

Abatacept Fails Clinical Trial for Sjögren’s Syndrome

March 24, 2020

The use of abatacept did not lead to significant improvements in the disease status of patients with primary Sjögren's syndrome and in fact, it was essentially no better than placebo treatment, shows the first randomized, double-blind trial on abatacept for Sjögren’s.

Secondary Sjögren’s Syndrome in Lupus Increases with Age

October 07, 2019

Sjögren’s syndrome secondary to systemic lupus erythematosus (SLE) rises in frequency with age, affects around one-quarter of all people with systemic lupus, and, despite less internal organ involvement than in systemic lupus without Sjögren’s syndrome, is marked by a systemic inflammatory state with high levels of pro-inflammatory cytokines, say researchers writing in The Journal of Rheumatology  this month.