RA Quiz: Measures of Mortality

July 1, 2020

Ingrid Torjesen

Ingrid Torjesen

Rheumatoid arthritis is not a life threatening condition per se, but it can have a dramatic impact on life expectancy. As a chronic systemic inflammatory condition, rheumatoid arthritis increases the risk of a number of other leading causes of death. Are you familiar with mortality risk in RA? Take this quiz.

SOURCES: (1) Widdifield J, Paterson M , Huang A , Bernatsky S. Causes of Death in Rheumatoid Arthritis: How Do They Compare to the General Population? Arthritis Care Res 2018;70(12):1748-1755. doi: 10.1002/acr.23548. (2). Sparks, J.A., Chang, S.‐C., Liao, K.P., Lu, B., Fine, A.R., Solomon, D.H., Costenbader, K.H. and Karlson, E.W. (2016), Rheumatoid Arthritis and Mortality Among Women During 36 Years of Prospective Follow‐Up: Results From the Nurses’ Health Study. Arthritis Care & Research, 68: 753-762. doi:10.1002/acr.22752. (3) van den Hoek J, Boshuizen HC, Roorda LD, et al. Mortality in patients with rheumatoid arthritis: a 15-year prospective cohort study. Rheumatol Int. 2017;37(4):487‐493. doi:10.1007/s00296-016-3638-5

SOURCES: (1) Widdifield J, Paterson M , Huang A , Bernatsky S. Causes of Death in Rheumatoid Arthritis: How Do They Compare to the General Population? Arthritis Care Res 2018;70(12):1748-1755. doi: 10.1002/acr.23548. (2). Sparks, J.A., Chang, S.‐C., Liao, K.P., Lu, B., Fine, A.R., Solomon, D.H., Costenbader, K.H. and Karlson, E.W. (2016), Rheumatoid Arthritis and Mortality Among Women During 36 Years of Prospective Follow‐Up: Results From the Nurses’ Health Study. Arthritis Care & Research, 68: 753-762. doi:10.1002/acr.22752. (3). van den Hoek J, Boshuizen HC, Roorda LD, et al. Mortality in patients with rheumatoid arthritis: a 15-year prospective cohort study. Rheumatol Int. 2017;37(4):487‐493. doi:10.1007/s00296-016-3638-5

SOURCES: (1) Widdifield, J. et al. Trends in Excess Mortality Among Patients With Rheumatoid Arthritis in Ontario, Canada. Arthritis Care Res 2016; 67: 1047–1053 (2015). (2). Widdifield J, Paterson M , Huang A , Bernatsky S. Causes of Death in Rheumatoid Arthritis: How Do They Compare to the General Population? Arthritis Care Res 2018;70(12):1748-1755. doi: 10.1002/acr.23548. (3) Houge, I.S., Hoff, M., Thomas, R. et al. Mortality is increased in patients with rheumatoid arthritis or diabetes compared to the general population – the Nord-Trøndelag Health Study. Sci Rep 10, 3593 (2020).

SOURCES: (1) Widdifield, J. et al. Trends in Excess Mortality Among Patients With Rheumatoid Arthritis in Ontario, Canada. Arthritis Care Res 2016; 67: 1047–1053 (2015). (2). Widdifield J, Paterson M , Huang A , Bernatsky S. Causes of Death in Rheumatoid Arthritis: How Do They Compare to the General Population? Arthritis Care Res 2018;70(12):1748-1755. doi: 10.1002/acr.23548. (3) Houge, I.S., Hoff, M., Thomas, R. et al. Mortality is increased in patients with rheumatoid arthritis or diabetes compared to the general population – the Nord-Trøndelag Health Study. Sci Rep 10, 3593 (2020).

SOURCES: (1) Widdifield J, Paterson M , Huang A , Bernatsky S. Causes of Death in Rheumatoid Arthritis: How Do They Compare to the General Population? Arthritis Care Res 2018;70(12):1748-1755. doi: 10.1002/acr.23548. (2) England, B.R., Sayles, H., Michaud, K., Caplan, L., Davis, L.A., Cannon, G.W., Sauer, B.C., Solow, E.B., Reimold, A.M., Kerr, G.S., Schwab, P., Baker, J.F. and Mikuls, T.R. (2016), Cause‐Specific Mortality in Male US Veterans With Rheumatoid Arthritis. Arthritis Care & Research, 68: 36-45. doi:10.1002/acr.22642. (3) Pedersen JK, Holst R, Primdahl J, Svendsen AJ, Hørslev-Petersen K. Mortality and its predictors in patients with rheumatoid arthritis: a Danish population-based inception cohort study. Scand J Rheumatol. 2018;47(5):371‐377. doi:10.1080/03009742.2017.1420223 (4) van den Hoek J, Boshuizen HC, Roorda LD, et al. Mortality in patients with rheumatoid arthritis: a 15-year prospective cohort study. Rheumatol Int. 2017;37(4):487‐493. doi:10.1007/s00296-016-3638-5

SOURCES: (1) Widdifield J, Paterson M , Huang A , Bernatsky S. Causes of Death in Rheumatoid Arthritis: How Do They Compare to the General Population? Arthritis Care Res 2018;70(12):1748-1755. doi: 10.1002/acr.23548. (2) England, B.R., Sayles, H., Michaud, K., Caplan, L., Davis, L.A., Cannon, G.W., Sauer, B.C., Solow, E.B., Reimold, A.M., Kerr, G.S., Schwab, P., Baker, J.F. and Mikuls, T.R. (2016), Cause‐Specific Mortality in Male US Veterans With Rheumatoid Arthritis. Arthritis Care & Research, 68: 36-45. doi:10.1002/acr.22642. (3) Pedersen JK, Holst R, Primdahl J, Svendsen AJ, Hørslev-Petersen K. Mortality and its predictors in patients with rheumatoid arthritis: a Danish population-based inception cohort study. Scand J Rheumatol. 2018;47(5):371‐377. doi:10.1080/03009742.2017.1420223. (4). van den Hoek J, Boshuizen HC, Roorda LD, et al. Mortality in patients with rheumatoid arthritis: a 15-year prospective cohort study. Rheumatol Int. 2017;37(4):487‐493. doi:10.1007/s00296-016-3638-5

SOURCES: (1). Simard JF, Ekberg S, Johansson AL, Askling J. What is the impact of chronic systemic inflammation such as rheumatoid arthritis on mortality following cancer?. Ann Rheum Dis. 2016;75(5):862‐866. doi:10.1136/annrheumdis-2014-207155. (2) Pincus T. Rheumatoid arthritis: Predicting mortality in RA: the quest for useful information. Nat Rev Rheumatol. 2015 Sep;11(9):507-9. doi: 10.1038/nrrheum.2015.89. Epub 2015 Jun 30. (3) Park, J.K., Yang, J.A., Ahn, E.Y. et al. Survival rates of cancer patients with and without rheumatic disease: a retrospective cohort analysis. BMC Cancer 16, 381 (2016). https://doi.org/10.1186/s12885-016-2444-5

SOURCES: (1) Simard JF, Ekberg S, Johansson AL, Askling J. What is the impact of chronic systemic inflammation such as rheumatoid arthritis on mortality following cancer?. Ann Rheum Dis. 2016;75(5):862‐866. doi:10.1136/annrheumdis-2014-207155 (2) Pincus T. Rheumatoid arthritis: Predicting mortality in RA: the quest for useful information. Nat Rev Rheumatol. 2015 Sep;11(9):507-9. doi: 10.1038/nrrheum.2015.89. Epub 2015 Jun 30. (3) Park, J.K., Yang, J.A., Ahn, E.Y. et al. Survival rates of cancer patients with and without rheumatic disease: a retrospective cohort analysis. BMC Cancer 16, 381 (2016). https://doi.org/10.1186/s12885-016-2444-5

SOURCES: (1) Sun, Zhuo MD; Hesler, Brian D. MD; Makarova, Natalya MS†; Dalton, Jarrod E. PhD†; Doan, Michael MD‡; Moraska, Amanda MD‡; De Oliveira, Gildasio MD§; Turan, Alparslan MD* The Association Between Rheumatoid Arthritis and Adverse Postoperative Outcomes: A Retrospective Analysis, Anesthesia & Analgesia: June 2016 - Volume 122 - Issue 6 - p 1887-1893 doi: 10.1213/ANE.0000000000001066. (2) Michaud K, Fehringer EV, Garvin K, O’Dell JR, Mikuls TRRheumatoid arthritis patients are not at increased risk for 30-day cardiovascular events, infections, or mortality after total joint arthroplasty.Arthritis Res Ther201315R195

SOURCES: (1) Sun, Zhuo MD; Hesler, Brian D. MD; Makarova, Natalya MS†; Dalton, Jarrod E. PhD†; Doan, Michael MD‡; Moraska, Amanda MD‡; De Oliveira, Gildasio MD§; Turan, Alparslan MD* The Association Between Rheumatoid Arthritis and Adverse Postoperative Outcomes: A Retrospective Analysis, Anesthesia & Analgesia: June 2016 - Volume 122 - Issue 6 - p 1887-1893 doi: 10.1213/ANE.0000000000001066. (2) Michaud K, Fehringer EV, Garvin K, O’Dell JR, Mikuls TRRheumatoid arthritis patients are not at increased risk for 30-day cardiovascular events, infections, or mortality after total joint arthroplasty.Arthritis Res Ther201315R195